TNF Blocker Injuries

What are Humira, Enbrel, Cimzie, Remecade prescribed for?sssss

All four drugs are TNF blockers which block the action of a substance in your body called TNF-alpha. TNF-alpha (tumor necrosis factor alpha) is made by your body’s immune system. People with Rheumatoid arthritis (RA) have too much of it in their bodies and attack normal healthy body tissues and cause inflammation especially in the tissues in your bones, cartilage and joints. TNF blockers help reduce the signs and symptoms of RA.. All four drugs are used to treat rheumatoid arthritis, psoriatic arthritis, plaque psoriasis, polyarticular juvenile idiopathic arthritis, Crohn’s disease and ankylosing spondylitis. If you, or someone you love, have been injured using Humira, Enbrel, Cimzie and/or Remecade and would like the attorneys at Nolan Law Group to review your case, please contact us.

What are the harmful side effects to be cautious of?

1. INFECTIONS TNF blockers decrease the body’s ability to fight infection, thus increasing the chances that a patient will develop a serious and potentially deadly infection. Some patients have died when the bacteria that cause infections have spread throughout their body (sepsis). Serious infections include aspergillosis, candidiasis and tuberculosis. On September 4, 2008, the FDA has received reports of patients developing pulmonary and disseminated histoplasmosis, coccidioidomycosis, blastomycosis and other opportunistic infections while taking TNF blockers. Signs and Symptoms of possible systemic fungal infection:
  • fever
  • malaise
  • weight loss
  • sweats
  • cough
  • dyspnea
  • pulmonary infiltrates
  • serious systemic illness with or without concomitant shock
Signs of Tuberculosis include:
  • chest pain
  • difficulty breathing
  • cough
  • sore throat
  • flu-like symptoms
  • weight loss
  • loss of appetite
  • night sweats
(Before administering TNF blocker, physicians should perform a skin test on a patient to ensure they do not have an inactive TB infection) Patients with the following risk factors are more likely to suffer a serious infection:
  • history of immune disease (AIDS, HIV, cancer or severe combined immunodeficiency syndrome (SCID)
  • history of recurring or chronic infection, or active infection such as cold sores, infections, etc.
  • concurrent use of immunosuppressnat drugs, such as oral cordicosteroids, chemotherapy drugs, cyclosporing, tacrolimus, sirolimus or similar medicaions
  • older age
  • history of Hepatitis B
2. MALIGNANCIES There have been cases of certain kinds of cancer in patients taking TNF blockers with rheumatoid arthritis, especially more serious rheumatoid arthritis, may have a higher chance for getting a kind of cancer called lymphoma. Some patients on TNF blockers have developed types of cancer called non-melanoma skin cancer (basal call cancer and squamous call cancer) which are generally not life threatening if treated. You must tell your physician if you have bump or open sore that doesn’t heal. If you, or someone you love, have been injured using Humira, Enbrel, Cimzie and/or Remecade and would like the attorneys at Nolan Law Group to review your case, please contact us.

What does the FDA say?

The Food and Drug Administration ordered stronger warnings September 4, 2008 on the four medications (Humira, Enbrel, Cimzie, Remecade) widely used to treat rheumatoid arthritis and other serious illnesses, saying they can raise the risk of possibly fatal fungal infections. In addition to the stronger warnings, the FDA also informed healthcare professionals that there is a possible association between drugs that block TNF and the development of lymphoma and other cancers in children and young adults. The TNF blockers in question are REMICADE, ENBREL, HUMIRA AND CIMZIA. If you, or someone you love, have been injured using Humira, Enbrel, Cimzie and/or Remecade and would like the attorneys at Nolan Law Group to review your case, please contact us.

What are your legal rights?

If you or someone you love have been injured from the use of Humira, Enbrel, Cimzie and/or Remecade you have the right to file a legal claim. Our attoneys can help you determine if you have a case and how to file a claim. All claims are handled on a contingency fee basis, meaning you do not have to pay attorney fees unless you are awarded compensation. If you would like the attorneys at Nolan Law Group to review your case, please contact us.
 

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